ERD8 — Brachypodium distachyon

Summary

BdERD8 (BRADI_3G39630V3) on Brachypodium distachyon chromosome 3 encodes a member of the heat shock protein 90 (Hsp90) family, characterized by Hsp90_N, Hsp90_C, and HATPase domains, and annotated with ATP-dependent protein folding chaperone activity, transcription regulator activity, and ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase activity. The gene is associated with diverse biological processes including cellular response to brassinosteroid stimulus, photoentrainment of the circadian clock, auxin metabolism, root hair cell differentiation, and leaf proximal/distal pattern formation. It has been linked to traits such as maturity time, photoperiod-sensitive flowering, seed viability, stamen length, and responses to downy mildew, aphids, and viral disease. Localization evidence connects the product to the chloroplast outer membrane, ER lumen, vesicle, and proteasome. Studies of related Hsp90 family members in other species link the family to heat tolerance, drought memory, pathogen resistance, and grain weight.