CIN4 — Brachypodium distachyon

Summary

BdCIN4 (BRADI_1G23630V3) on Brachypodium distachyon chromosome 1 encodes a protein with a UBC domain and ubiquitin-conjugating enzyme activity, and is associated with histone H2B deubiquitinase activity, metallopeptidase activity, calmodulin binding, nucleic acid binding, ubiquitin ligase activity, ubiquitin-protein transferase activity, ATP hydrolase activity, protein kinase activity, and identical protein binding. It is associated with DNA damage tolerance, protein polyubiquitination, proteasomal protein catabolic process, COP9 signalosome assembly, endosomal transport, and regulation of photomorphogenesis and entrainment of circadian clock. The gene is linked to responses to abscisic acid, anthocyanin metabolism, and photoperiod-sensitive flowering time. Traits connected to BdCIN4 include boron sensitivity, UV light sensitivity, drought stress response, stomatal closure, seed dormancy, leaf senescence, salt stress tolerance, and phosphate uptake. Studies of related genes in other species link the family to photomorphogenesis, circadian clock entrainment, cell cycle progression, and stress tolerance, while rice studies connect it to defense.