PCNA — Beta vulgaris subsp. vulgaris

Summary

BvPCNA (BVRB_7G172880) on sugar beet chromosome 7 encodes a proliferating cell nuclear antigen (PCNA), a processivity clamp with DNA-directed DNA polymerase activity, damaged DNA binding, SUMO transferase activity, SUMO binding, chromatin binding, protein phosphorylated amino acid binding, kinase binding, DNA binding, and protein binding. This gene is associated with bypass DNA synthesis, DNA repair-dependent chromatin remodeling, leading strand elongation, phagocytosis, mutagenic PRR, swimming, upregulation of apoptosis, mitotic DNA replication, anti-apoptosis, regulation of DNA replication, ICL repair, protein homotrimerization, MMR, double-strand break repair via synthesis-dependent strand annealing, DNA anabolism, UV protection, HDR, and metabolic burst. BvPCNA is linked to radiation response, UV light sensitivity, plant tissue development, pollen fertility restoration, cell cycle, plant stress response, stomatal opening, oxidative stress response, abscisic acid sensitivity, flowering time, plant growth and development, root morphology, and SALTTL traits. The protein localizes to the PCNA complex, apoplast, nucleolus, chloroplast stroma, plant-type vacuole, Golgi complex, plasmodesma, cytosol, and plasmalemma. Studies of related genes in other species connect the PCNA family to DNA repair, gamma radiation sensitivity, cadmium response, silver nanoparticle response, UV resistance, female germ