HRD1 — Beta vulgaris subsp. vulgaris
Summary
BVRB_3G049980 (HRD1) on sugar beet chromosome 3 encodes a RING-type E3 ubiquitin ligase with zinc-binding activity, belonging to the HRD1 family of ER membrane proteins. The gene is associated with the endoplasmic reticulum-associated degradation (ERAD) pathway, protein ubiquitination, and proteasomal degradation, and its product localises to the endomembrane system and ER membrane. Related genes in other species link the family to ubiquitin ligase activity (EC 2.3.2.27).
Annotations
- Chromosome
- 3
- GO terms
- proteasomal pathway, Zn binding, ER membrane, Endomembrane System, ubiquitin ligase activity, Protein Ubiquitination, ERAD Pathway
- Publications
- PMID:18089549, PMID:24280374, PMID:19282840, PMID:41481767