PPAR — Beta vulgaris subsp. vulgaris

Summary

BVRB_011540 (PPAR) on sugar beet chromosome 0326.scaffold00811 encodes an uncharacterized protein with D-isomer-specific 2-hydroxyacid dehydrogenase catalytic and NAD-binding domains, annotated with multiple oxidoreductase activities including glyoxylate reductase (NADH and NADPH), hydroxypyruvate reductase (NADPH), glycerate dehydrogenase, formate dehydrogenase, and D-lactate dehydrogenase activities. The gene is associated with the oxidative photosynthetic carbon pathway, cellular respiration, gluconeogenesis, fatty acid oxidation, formate breakdown, and phosphoglyceride metabolism, as well as glucose and cholesterol metabolism, lipogenesis, and hormone anabolism. It is linked to mitochondrial and cytosolic localisation and to nitrate content. Studies of related genes in other species connect the family to formate dehydrogenase (FDH), glycerate dehydrogenase (GDH), and hydroxypyruvate reductase (HPPR) functions, with EC numbers 1.1.1.28, 1.1.1.29, 1.1.1.79, 1.1.1.110, 1.1.1.237, and 1.17.1.9.