PFG1 — Arabidopsis thaliana

Summary

AT2G47460, also known as PFG1 or MYB12, encodes a protein containing a Myb DNA-binding domain. The protein localises to the nucleus and exhibits transcription cis-regulatory region binding and DNA-binding transcription factor activity. In Arabidopsis, MYB12 is associated with flavonol and flavonoid accumulation, phenylpropanoid metabolism, and tolerance to drought, salt, and UV-B stress. It is also linked to defence against cyst nematodes, auxin transport, pigmentation, and secondary metabolism. Broader associations include seed shattering, fruit dry weight, petal colour, leaf and root morphology traits, proline and lignin content, and stress responses. Related genes in other species are associated with flavonoid metabolism, rutin production, polyphenol content, antioxidant capacity, and insect resistance.