BIG — Arabidopsis thaliana

Summary

AT3G02260, also known as BIG, TIR3, LPR1, UMB1, CRM1, and DOC1, encodes a protein containing UBR4-like, zinc finger, WD40 repeat, and ARM-type fold domains, and is annotated with SUMO transferase activity, SUMO binding, kinase binding, and protein binding. The gene is associated with biological processes including phototransduction, cytokinin breakdown, ER-phagy, cell wall thickening, and reactive oxygen species anabolism, and localizes to the plasmodesma, membrane, cytosol, and nucleus. BIG is associated with traits including biomass yield, flowering time, root length, pedicel length, leaf growth, auxin content, anthocyanin content, iron concentration, disease tolerance, insect resistance, and responses to abscisic acid, gibberellic acid, cytokinin, and aluminum. Phenotypic associations include auxin transport, root system architecture, phosphate sensing, lignin deposition, stomatal movement, and circadian period adjustment.