CLF — Arabidopsis thaliana

Summary

AT2G23380, known as CLF (CURLY LEAF) in Arabidopsis thaliana, encodes a SET-domain-containing protein with histone H3K27 trimethylase activity. The gene is associated with a wide range of developmental and regulatory processes, including flower development, embryonic patterning, seed development, parental imprinting, and the specification of adaxial/abaxial and proximal/distal axes. CLF has been linked to numerous agronomically relevant traits such as seed weight, harvest index, stem number, leaf morphology, photoperiod sensitivity, and responses to drought and cold stress. It is also connected to chromatin silencing, heterochromatin organization, and the regulation of gene expression through histone methylation. Studies of related genes in other species link the CLF family to fruit weight, seed volume, and transposon silencing.