GR (TRAESCS4D02G277400) — triticum aestivum

Summary

TRAESCS4D02G277400, designated TaGR on bread wheat chromosome 4D, encodes a glutathione reductase (EC 1.8.1.7) with additional annotated activities including dihydrolipoyl dehydrogenase, thioredoxin reductase, leghemoglobin reductase, and protein translocase functions. The product belongs to the GSHR/TRXR-like family and binds FAD, NADP, ATP, copper, and other metals. TaGR is associated with cell redox homeostasis, the ascorbate-glutathione cycle, glutathione metabolism, glycine decarboxylation, 2-oxoglutarate metabolism, and mitochondrial protein import. It localises to mitochondrial membranes, the glycine cleavage system, and chloroplast stroma. The gene is associated with stripe rust, photosynthetic rate, chlorophyll content, starch concentration and mobilization, seed germination, root morphology, cadmium concentration, cell membrane stability, and oxidative, salt, and drought stress tolerance. Related genes in other species are linked to redox homeostasis, sulfur assimilation, and stress tolerance.