IRT1 (TRAESCS4A02G294300) — triticum aestivum

Summary

TRAESCS4A02G294300, designated TaIRT1 on bread wheat chromosome 4A, encodes a member of the ZIP family of metal transporters with transmembrane transporter activity for copper, zinc, manganese, iron, and cadmium ions. The gene is associated with zinc accumulation, iron homeostasis, and responses to iron and zinc deficiency. It has been linked to grain yield, plant height, tiller number, root fresh weight, root length, grain filling period, and cadmium concentration. Associations also include nickel and cadmium transport, cellular and multicellular iron ion homeostasis, detoxification, downregulation of abscisic acid signalling, response to hypoxia, and cell wall organization. The protein localizes to the plasma membrane, endosome, late endosome membrane, and ESCRT I complex. Related genes in other species link the family to iron acquisition, cadmium uptake, and metal accumulation.

Annotations

Chromosome
4A
Related genes
IRT1, MADS1, IDF1, FREE1, IRT2, ZIP10, ZIP3, MYC2
GO terms
GO:0005575, homeostasis, Cadmium Ion Transmembrane Transporter Activity, multicellular organismal iron ion homeostasis, Endosome, Metal Ion Transmembrane Transporter Activity, Late Endosome Membrane, MRNA Binding
Publications
35077969, 26165498, 23794026, 29547723, 17404382, 16684236, 35755678, 31115467
Traits
iron uptake, iron deficiency response, iron acquisition, abscisic acid sensitivity, lipid droplet turnover, lipid droplet degradation, cadmium uptake, cadmium detoxification