HSC-2 (TRAESCS1D02G284000) — triticum aestivum

Summary

TRAESCS1D02G284000 (symbol HSC-2, also known as TaCTHSP70-1) on bread wheat chromosome 1D encodes an ATP-dependent protein folding chaperone of the Hsp70 family, with ATP hydrolase activity and heat shock protein binding capability. This gene is associated with protein processing, folding, and refolding in the endoplasmic reticulum, as well as the ERAD pathway and ER stress response. It is associated with grain protein content, grain size, grain weight, grain yield, starch content, and carotenoid content. Associations also include heat tolerance, drought tolerance, salt response, and abiotic stress tolerance. The gene is associated with salicylic acid signaling, hormone signaling and metabolism, and transcription of HSF1. Studies of related Hsp70 family members in other species link the family to spikelet fertility, grain yield per plant, and osmotic stress tolerance.