MYCGR3G110231 — Zymoseptoria tritici

Summary

MYCGR3G110231 (ERG11) on Zymoseptoria tritici chromosome 7 encodes a sterol 14-demethylase, a cytochrome P450 monooxygenase with heme and iron binding, oxidoreductase and methyltransferase activities. The gene is associated with ergosterol, sterol, mycotoxin, glycerol and heme anabolism, as well as demethylation, methylation, steroidogenesis, sterol import, cytokinesis, S phase, sporulation, fermentation, cell growth and homeostasis. The product localises to the endoplasmic reticulum membrane and membrane. Studies of related genes in other species link the gene family to reduced virulence and lethality, and sequence similarity connects the family to oxidative stress.