CRIP9 — Zea mays

Summary

ZM00001EB326540 (CRIP9) on maize chromosome 7 encodes an rRNA N-glycosylase (EC 3.2.2.22) with toxin activity. The gene is associated with depurination, negative regulation of translation, zymogen activation, secretion, and the viral life cycle, as well as cytidine-to-uridine editing, AMP metabolism, detoxification, and nitric oxide storage. It has been linked to anther and endosperm development, embryogenesis, cell wall organization, and response to insects. Trait associations include grain yield, drought tolerance, root volume, lateral root number, root length, root number, seed maturation, heterosis, and cytoplasmic male sterility. The encoded protein localizes to the cytoplasm. Studies of related genes in other species link the CRIP9 family to rRNA N-glycosylase activity and ribosome inactivation.