R1 — Zea mays

Summary

ZM00001EB271680 (ZmR1, also known as RNRL2, CLS8, DPD2, V3) on maize chromosome 6 encodes a ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1), an enzyme with ribonucleoside-diphosphate reductase activity that uses thioredoxin disulfide as acceptor and binds ATP. The protein belongs to the RNR_lsu_N, ATP-cone_dom, and RNR_lg_C domain families. This gene is associated with deoxyribonucleotide and deoxyribonucleoside triphosphate anabolism, DNA replication, anthocyanin and phenylpropanoid anabolism, pigmentation, and homeostasis. It has been connected to anthocyanin content, leaf morphology, plant growth and development, plastid DNA degradation, photosynthesis, chloroplast function, and crinkled leaves with bleached edges and asymmetric growth. The product localises to the cytoplasm and the RNR complex. Studies of related genes in other species link the family to DNA damage response and ribonucleotide reduction.