GAD — Triticum turgidum subsp. durum

Summary

TRITD3BV1G005920, designated TtGAD1, encodes a glutamate decarboxylase on durum wheat chromosome 3B. The enzyme possesses glutamate decarboxylase activity, calmodulin binding, and pyridoxal phosphate binding, and is localized to the cytosol and ER membrane. TtGAD1 is associated with the GABA shunt, glutamate and sphingolipid breakdown, carboxylic acid metabolism, mRNA transcription, response to water, seed germination, and homeostasis. It is linked to grain filling period, growth stage, germination rate, and photosynthetic rate. Related genes in other species connect the family to root, seed, and shoot phenotypes, as well as cold, salinity, and flooding tolerance. Sequence similarity further links the family to grain yield, grain length, drought tolerance, cold tolerance, and traits including reducing sugar, soluble protein, and amino acid content.