HMA2 — Triticum aestivum

Summary

TRAESCS7B02G320900 (TaHMA2) on chromosome 7B encodes an HMA domain-containing protein and a P-type ATPase of the IB subfamily, annotated with cation-transporting ATPase activity including P-type divalent and monovalent copper transporter activity, P-type zinc transporter activity, and cadmium exporting ATPase activity. The gene is associated with detoxification of cadmium and copper ions, copper and zinc ion homeostasis, response to cobalt ion, cell wall thickening, and detection of bacteria. It is linked to cadmium tolerance and cadmium sequestration in roots, as well as traits including root system cadmium content, grain yield, plant height, phosphorus concentration, and bacterial disease response. The encoded protein localises to the vacuolar membrane, Golgi membrane, plasmodesma, and plasmalemma. Studies of related genes in other species link the family to cadmium long-distance translocation and zinc transport.