Lr10 — Triticum aestivum

Summary

TRAESCS1D02G019600, the Lr10 gene on bread wheat chromosome 1D, encodes an NB-ARC domain-containing protein with ADP, ATP and metal binding activities. This gene is associated with leaf rust resistance, a phenotype observed directly in wheat. It is linked to immune response, regulation of pattern recognition receptor signaling, innate immune response-activating signaling, hypersensitive response cell death, defense responses to bacteria and other organisms, cell death, signal transduction, chloroplast organization, cellular homeostasis, transport, cell communication, and lipid metabolism. The encoded protein localises to the cytosol and cytoplasm. Associations with stem rust, growth stage, and powdery mildew resistance have also been noted. Studies of related genes in other species link the family to rice leaf blast and wheat powdery mildew disease responses.