ADH — Sorghum bicolor

Summary

SbADH (SORBI_3002G379200) on sorghum chromosome 2 encodes an enoyl reductase domain-containing protein with S-(hydroxymethyl)glutathione dehydrogenase, S-nitrosoglutathione reductase, and aldo-keto reductase activities, along with calcium, zinc, and metal binding and protein homodimerization activity. The gene is associated with responses to hypoxia, flooding, hydrogen peroxide, heat acclimation, and osmotic and salinity stress, as well as seed development, programmed cell death, cell wall modification, and cellular respiration. It has been linked to traits including plant height, stem thickness, photosynthetic and respiration rates, leaf senescence, drought tolerance, herbicide sensitivity, disease tolerance, and salt tolerance. The encoded protein localizes to plastids, mitochondria, cytosol, nucleus, and plasma membrane. Studies of related genes in other species link the family to hypoxia, cold, drought, and salt stress responses, submergence tolerance, and formaldehyde detoxification.