DNAJ — Solanum tuberosum

Summary

PGSC0003DMG400023400 (DNAJ) on potato chromosome 5 encodes a DnaJ-like protein, a member of the HSP40/DnaJ chaperone family that possesses ATPase activator activity, binds Hsp70 and heat shock proteins, and also binds mRNA, ATP, and zinc. The gene is associated with responses to heat, water, and growth hormone, as well as with protein folding in the endoplasmic reticulum, protein refolding, oxidative phosphorylation, fatty acid beta-oxidation, and the metabolism of lysine, amino acids, RNA, lignin, carotenoids, and pigments. It has been linked to traits including drought tolerance, salt response, stomatal resistance and opening, and to starch concentration, reducing sugar content, starch yield, starch content, sugar content, and carotenoid content. The encoded protein localises to the ER lumen, ER, membrane, cytosol, plasmalemma, cytoplasm, and nucleus. Studies of related genes in other species further connect the family to chaperone functions.