CYP51 — Solanum tuberosum

Summary

StCYP51, located on potato chromosome 1, encodes a cytochrome P450 family protein with sterol 14-demethylase activity (EC 1.14.14.154), as well as protopanaxadiol 6-hydroxylase and abscisic acid 8'-hydroxylase activities. The gene is associated with sterol metabolism and anabolism, the mevalonate (MVA) pathway, abscisic acid breakdown, saponin and terpenoid anabolism, wound healing, fruit ripening, and response to molecules of fungal origin. It has been linked to membrane integrity, sterol biosynthesis, stomatal development, seedling growth and viability, hypocotyl elongation, leaf senescence, chloroplast development, and oxidative stress tolerance. The encoded protein localises to the endoplasmic reticulum, Golgi complex, and membrane. Studies of related genes in other species connect it to plant height, life span, seedling growth, and aluminum tolerance.