BIP5 — Solanum tuberosum

Summary

PGSC0003DMG400012254, symbol BIP5, on potato chromosome 8 encodes a member of the Hsp70 family of molecular chaperones, possessing ATP hydrolase activity, ATP binding, heat shock protein binding and protein folding chaperone functions. The gene is associated with the endoplasmic reticulum (ER) chaperone complex and ER lumen, as well as the tonoplast, cytoplasm, nucleus and membrane. BIP5 is associated with protein folding in the ER, the ERAD pathway, the ER unfolded protein response (erUPR), ER stress response, autophagy, protein maturation and refolding, cellular homeostasis, RNA metabolism and splicing, protein synthesis, glycan and cell wall polysaccharide biosynthesis, regeneration, detoxification, and responses to UV and UV-A. Related genes in other species link the family to the ER chaperone complex and ATP hydrolase activity (EC 3.6.4.10).