SHD — Solanum tuberosum

Summary

StSHD (PGSC0003DMG400009509) on potato chromosome 3 encodes a heat shock protein 90 (Hsp90) family chaperone with ATP-dependent protein folding activity. In potato, StSHD is associated with temperature stress tolerance and PVY susceptibility. The gene has been linked to diverse biological processes including cellular response to unfolded protein, vesicle organization, base-excision repair, proline metabolism, regulation of flavonoid anabolism, and respiratory burst in defense response. It localizes to multiple cellular compartments including the ER lumen, chloroplast outer membrane, and plasma membrane. StSHD is associated with numerous agronomic traits including reducing sugar content, starch grain synthesis, plant fresh weight, root dry weight, seed set, submergence tolerance, and responses to bacterial, viral, and downy mildew diseases. Studies in related genes in other species link the Hsp90 family to salinity tolerance, root biomass, and resistance to yellow leaf curl virus, as well as thermotolerance, broad-spectrum disease resistance, and chloroplast function.