HSP70 — Solanum tuberosum

Summary

PGSC0003DMG400008698 (HSP70) on potato chromosome 6 encodes a heat shock protein 70 (Hsp70) family member with ATP hydrolase activity, ATP binding, heat shock protein binding, and protein folding chaperone functions. This gene is associated with protein refolding, the ERAD pathway, the unfolded protein response, nucleosome assembly, and responses to heat, stress, and virus infection, including virus-induced post-transcriptional gene silencing. It is linked to sterol, sucrose, fatty acid, and lipid metabolism, detoxification, immune response, nitric oxide storage, chlorophyll fluorescence, cell division, and photosynthetic rate, including net photosynthetic rate and proline content. The protein localises to the cytoplasm, nucleus, membrane, chloroplast membrane, ER lumen, ER chaperone complex, and axonemal central pair projection. Studies of related genes in other species link this family to endoplasmic reticulum stress responses and protein quality control.