M2 — Solanum tuberosum

Summary

StM2 (M2, CYP22) on potato chromosome 1 encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase) with cyclosporin A binding, peroxidase activity, and additional annotated molecular functions including GTP:GDP antiporter activity, U5 and U2 snRNA binding, L-serine O-acetyltransferase activity, salicylic acid binding, and histone and chromatin binding. The gene is associated with protein proline isomerization, regulation of ARF protein signal transduction, chaperone-mediated protein complex assembly, alternative mRNA splicing, wound healing, response to light intensity and sulfate starvation, and endosome transport. It is linked to numerous traits including variegated leaf, starch grain synthesis, respiration rate, photosynthetic rate, sucrose content, temperature stress response, herbicide sensitivity, root hair length, root mass density, chloroplast development, jasmonic acid content, and plant stress responses. Localization evidence connects the product to the Golgi stack, thylakoid lumen, stromule, secretory vesicle, and proteasome. Related genes in other species link the family to water stress tolerance, cold stress response, hydrotropism, phototropism, and embryo patterning.