ACO3 — Solanum lycopersicum

Summary

SlACO3 (SOLYC12G006380.2) on tomato chromosome 12 encodes a 2-oxoglutarate-dependent dioxygenase, a member of the IPNS-like Fe2OG oxygenase family. The enzyme exhibits oxidoreductase activity acting on paired donors with 2-oxoglutarate, and is annotated with multiple dioxygenase activities including flavonol synthase and flavanone 3-dioxygenase. SlACO3 is associated with flavonol and flavonoid metabolism, auxin and salicylic acid breakdown, strigolactone and lycopene anabolism, and response to iron(III). The gene has been linked to fruit diameter, weight, shape, size, firmness, and lycopene and carotenoid content, as well as leaf and stem dimensions, plant height, ethylene sensitivity, germination rate, and stomatal resistance. It localises to the cytoplasm and nucleus. Studies of related genes in other species connect the family to anthocyanidin synthase and deoxymugineic acid dioxygenase activities.