ROS1A — Solanum lycopersicum

Summary

SOLYC10G083630.2, also known as ROS1A, is a tomato gene on chromosome 10 that encodes a DNA glycosylase with DNA demethylase activity, acting on 5-methylcytosine. The protein contains Perm-CXXC, RRM_DME, and HhH-GPD domains and binds a 4Fe-4S cluster. ROS1A is associated with chromosomal 5-methylcytosine DNA demethylation pathways, DNA modification, and the direct excision of 5-methylcytosine. It is also linked to carotenoid and cytokinin breakdown, pigment accumulation, flower formation, tube formation, and tracheary element differentiation. Associations with agronomic traits include fruit firmness, fruit color, fruit size, anthocyanin content, leaf length, plant height, proline content, salt response, stomatal opening, and drought tolerance. The protein localises to the nucleus. Related genes in other species link the family to additional DNA glycosylase functions.