GR1 — Solanum lycopersicum

Summary

SlGR1 (SOLYC09G091840.4) encodes a protein with leghemoglobin reductase, dihydrolipoyl dehydrogenase (NADH), glutathione reductase, and thioredoxin reductase (NADPH) activities, and binds NADP and FAD. It belongs to the GSHR/TRXR-like family and localises to mitochondria, the cytosol, and the glycine cleavage system. SlGR1 is associated with lycopene breakdown, the ascorbate-glutathione cycle, glutathione anabolism, oxygen metabolism, nitrogen fixation, vitamin A anabolism, and upregulation of photosynthesis. It has been linked to fruit color, lycopene and carotenoid content, fruit weight, leaf chlorophyll content, net photosynthetic rate, biomass yield, water use efficiency, and salt response. Phenotypic associations include oxidative stress response and resistance, cadmium and ozone tolerance, glutathione biosynthesis, salicylic acid accumulation, and jasmonic acid signaling. Studies of related genes in other species link the family to cellular redox homeostasis, oxidative stress, salinity, drought, cold, heat, and submergence tolerance, as well as cell cycle regulation and glutathione accumulation.