AS1 — Solanum lycopersicum

Summary

SlAS1 (SOLYC06G007180.3) encodes an asparagine synthase (glutamine-hydrolyzing) with ATP-binding activity, belonging to the AsnB_N and Asn_synthase domain families. In tomato, this gene is associated with L-asparagine anabolism, amino acid breakdown, nitrogen fixation, cellular response to sucrose starvation, and regulation of secondary metabolite biosynthesis and signal transduction. It localizes to the cytosol and cytoplasm. SlAS1 has been linked to agronomically important traits including fruit size, leaf shape and size, specific leaf weight, root number and length, nitrate and sugar content, protein content, stomatal resistance, and leaf chlorosis. The gene is also connected to nitrogen metabolism, leaf senescence, and tolerance to nitrogen-limiting, phosphate starvation, and salt stress conditions. Studies of related genes in other species link the family to seed nitrogen content and acrylamide formation.