HSP70 — Pisum sativum

Summary

PSAT7G005760 (HSP70) on garden pea chromosome 7LG7 encodes a member of the Hsp70 family, a heat shock protein binding chaperone with ATP hydrolase activity and ATP binding. The product contains an ATPase NBD and a leucine-rich repeat domain superfamily. This gene is associated with protein folding in the endoplasmic reticulum, mitochondrial protein import, the ERAD pathway, the unfolded protein response, and S-nitrosylation. It has been linked to seed maturation, embryogenesis, cell development, DNA replication, and response to virus and stress. Localisation evidence connects the protein to the ER lumen, ER chaperone complex, chloroplast membrane, tonoplast, cytoplasm, and nucleus. Studies of related genes in other species link the family to ER stress responses and protein quality control.