LIP1 — Pisum sativum

Summary

PSAT5G270520 (symbol LIP1) on garden pea chromosome 5LG3 encodes a lipoic acid synthase (EC 2.8.1.8), a mitochondrial enzyme that binds 4Fe-4S clusters and metal ions. The gene is associated with lipoate anabolism, protein lipoylation, and glycine breakdown, as well as with photomorphogenesis, skotomorphogenesis, and dark adaptation. LIP1 is also linked to strigolactone anabolism and response to strigolactone, response to auxin, signal transduction, and response to stress. Additionally, it is linked to regulation of response to thirst. The encoded protein localises to the mitochondrial lumen and mitochondria. Related genes in other species link the family to similar lipoate-related functions.