PCNA — Pisum sativum

Summary

PSAT5G162720 (PCNA) encodes proliferating cell nuclear antigen, a processivity clamp that also exhibits histone H3K27 methylase activity, DNA-directed DNA polymerase activity, damaged DNA binding, SUMO transferase activity, and chromatin binding. In garden pea, this gene is associated with DNA repair-dependent chromatin remodeling, bypass DNA synthesis, leading strand elongation, cell cycle checkpoint, mitotic DNA replication, mismatch repair, UV protection, and regulation of metabolism. It localizes to the PCNA complex, nucleolus, chloroplast stroma, plasmodesma, and apoplast. PCNA is linked to traits including radiation response, UV light sensitivity, oxidative stress response, abscisic acid sensitivity, flowering time, root morphology, stomatal opening, and salt tolerance. Phenotype associations include DNA damage tolerance, nuclear genome stability, heterochromatin condensation, transposon silencing, and male fertility. Related genes in other species are linked to DNA replication, cadmium response, immune response, and thermo-resilience.