HSP70 — Pisum sativum

Summary

PSAT4G210520 (HSP70, PsHSP70-8) on chromosome 4LG4 encodes a heat shock 70 kDa protein family member with an HSP70 peptide-binding domain, an Hsp70 family domain, and an ATPase nucleotide-binding domain. The product has ATP hydrolase activity, binds ATP, acts as a protein folding chaperone, and binds heat shock proteins. It is associated with protein folding in the endoplasmic reticulum, the ERAD pathway, the unfolded protein response, mitochondrial protein import and biogenesis, S-nitrosylation, seed maturation, embryogenesis, response to virus, and response to stress. Localisation evidence links it to the ER lumen and chaperone complex, chloroplast membrane, tonoplast, cytoplasm, and nucleus. Studies of related genes in other species connect the HSP70 family broadly to stress tolerance and protein homeostasis.