HSP70 — Pisum sativum

Summary

PSAT3G106800 (HSP70) in garden pea (Pisum sativum, chromosome 3LG5) encodes a member of the Hsp70 family, characterized by an ATPase nucleotide-binding domain. The product possesses ATP hydrolase activity, ATP binding, heat shock protein binding, and is annotated as a protein folding chaperone. This gene is associated with a wide range of biological processes, including protein folding and refolding, mitochondrial protein import and biogenesis, the ER unfolded protein response (erUPR), ERAD pathway, S-transnitrosylation and S-nitrosylation, DNA replication, cell development, embryogenesis, seed maturation, and response to stress and viruses. It localizes to the cytoplasm, nucleus, membrane, chloroplast membrane, ER lumen, ER chaperone complex, and axonemal central pair projection. Studies of related genes in other species link the family to similar chaperone and stress-response functions.