GYRB — Pisum sativum

Summary

PsGYRB1 (PSAT3G079040) on garden pea chromosome 3LG5 encodes a DNA gyrase subunit B, a type II topoisomerase with DNA negative supercoiling activity, DNA topoisomerase type II activity, and ATP and metal binding. The protein contains Topo_IIA_B, TOPRIM_GyrB, and HATPase domains. It is associated with DNA topological change, sister chromatid segregation, resolution of meiotic recombination intermediates, and nodulation. The product localises to the chloroplast nucleoid, mitochondria, nucleus, and cytoplasm. PsGYRB1 is linked to root morphology traits and to ciprofloxacin resistance with normal chloroplast morphology. Related genes in other species are linked to ciprofloxacin resistance.