HSP70 — Pisum sativum

Summary

PSAT2G037160 (HSP70) on garden pea chromosome 2LG1 encodes a member of the heat shock protein 70 family, characterized by an ATPase nucleotide-binding domain and heat shock 70 conserved signature. The product has ATP hydrolase activity, binds ATP, acts as a protein folding chaperone, and exhibits heat shock protein binding activity. This gene is associated with protein folding and refolding, protein import and targeting, mitochondrial biogenesis and protein import, the ER unfolded protein response, ERAD pathway, S-nitrosylation and S-transnitrosylation, DNA replication, cell development, embryogenesis, seed maturation, response to stress, and response to virus. It is linked to localization in the cytoplasm, nucleus, membrane, chloroplast membrane, ER lumen, ER chaperone complex, and axonemal central pair projection. Studies of related genes in other species connect the family to ER chaperone functions.