RIN4 — Phaseolus vulgaris

Summary

PHAVU_008G130600 (PvRIN4) on chromosome 8 of French bean encodes a RIN4/NOI4 family protein with a Type III avirulence cleavage domain and annotated molecular functions including clathrin light chain binding, proton-transporting ATPase activity, and cis-trans proline isomerase activity. The gene is associated with detection of bacteria, negative regulation of the hypersensitive response, PTI signalling, defense response by callose deposition, and response to molecules of bacterial origin. It is linked to lipid raft localization, receptor-mediated endocytosis, regulation of protein phosphorylation, and blue and red/far-red light signaling pathways. Associations with agronomic traits include bacterial disease response, bacterial blight disease resistance, water use efficiency, transpiration rate, root hair length, stomatal closure time, leaf senescence, shoot branching, and responses to aluminum, cadmium, and low temperature stress. Studies of related genes in other species link the family to innate immune response, resistance to Pseudomonas syringae, broad-spectrum disease resistance, and plasma membrane H+-ATPase activity.