ALS — Phaseolus vulgaris

Summary

PHAVU_006G187400, designated PvALS, encodes an acetolactate synthase (ALS) on chromosome 6 of French bean (Phaseolus vulgaris). The product possesses acetolactate synthase, 2-hydroxyacyl-CoA lyase, and pyruvate decarboxylase activities, binds thiamine pyrophosphate, FAD, and magnesium, and localises to the chloroplast stroma as part of the acetolactate synthase complex. PvALS is associated with branched-chain amino acid biosynthesis, valine anabolism, fatty acid alpha-oxidation, and response to herbicide. A specific G121A substitution links the gene to herbicide tolerance. Related genes in other species are associated with herbicide resistance, enzyme stability, seed production, seed weight, nitrogen content, plant height, and salt response.