ALDH22A1 — Phaseolus vulgaris

Summary

PHAVU_003G113500, symbol ALDH22A1, encodes an aldehyde dehydrogenase domain-containing protein on chromosome 3 of French bean (Phaseolus vulgaris). The product exhibits multiple aldehyde dehydrogenase activities, including succinate-semialdehyde dehydrogenase (NAD+) activity, betaine-aldehyde dehydrogenase (NAD+) activity, and aminobutyraldehyde dehydrogenase (NAD+) activity, and binds Na+ and K+ ions. The gene is associated with GABA catabolism, cellular response to anoxia, alkanal metabolism, and cellular detoxification of aldehyde. It localizes to the mitochondrial lumen, endoplasmic reticulum, and cytoplasm. Studies of related genes in other species link the ALDH22A1 family to aldehyde dehydrogenase functions, though these associations are not established for this specific gene.