BADH — Oryza sativa Japonica

Summary

Rice gene BADH (ALDH2a, Os06g0270900) encodes an aldehyde dehydrogenase family protein with oxidoreductase activity acting on aldehyde or oxo-group donors, utilizing NAD or NADP as acceptor. It exhibits multiple aldehyde dehydrogenase activities including acetaldehyde, phenylacetaldehyde, coniferyl-aldehyde, benzaldehyde, and succinate-semialdehyde dehydrogenase activities. The gene is associated with grain fragrance and aroma, grain size, male sterility, and resistance to fungal blast. It is associated with submergence tolerance, salinity and drought stress responses, and temperature tolerance. Associations include ethanol and glycine betaine metabolism, GABA catabolism, cellular detoxification of aldehydes, fermentation, and the GABA shunt. The protein localizes to mitochondria, vacuole, apoplast, chloroplast stroma, endoplasmic reticulum, and Golgi complex. Studies of related genes in other species link the family to glycine betaine synthesis, oxidative stress tolerance, and leaf adaxial-abaxial polarity.