AFB1 — Oryza sativa Japonica

Summary

OS05G0150500 (AFB1, also known as TIR1) encodes an F-box and leucine-rich repeat-containing protein that exhibits NEDD8 transferase, ubiquitin-like protein transferase, auxin influx/efflux transmembrane transporter, and ABC-type indole transporter activities. In rice, AFB1 is associated with defense, drought and salt stress responses, phosphate homeostasis, tillering, flower development, and growth. It is linked to the regulation of defense response by callose deposition, cellular response to nitrate, establishment of planar polarity, SCF complex assembly, and indole glucosinolate breakdown. The protein localizes to the nuclear SCF complex and ubiquitin ligase complex. Studies of related genes in other species link the family to auxin sensitivity, lateral root formation, inflorescence branching, and herbicide resistance.