PMIT1 — Oryza sativa Japonica

Summary

OsPMIT1 (also known as OsNRAMP1, OsNRAMP2, OsNRAMP3, OsNRAMP5, and OsNRAMP6) on rice chromosome 3 encodes a member of the NRAMP family of metal ion transporters, with molecular functions including manganese, iron, and cadmium ion transmembrane transporter activity. The gene is associated with a wide range of metal-related processes, including manganese and iron homeostasis, cadmium transport and accumulation, and responses to metal toxicity. In rice, the family has been linked to cobalt accumulation and tolerance, iron uptake, immunity and disease resistance, and grain cadmium content, yield, and quality. Additional associations include biological yield, leaf relative water content, amino acid content, shoot and root dry weight, chlorophyll content, plant height, and grain yield. The encoded protein localizes to the tonoplast, trans-Golgi network, endosome, and vacuolar membranes, and is linked to phloem loading, pectin anabolism, and regulation of vacuolar transport.