DA2 — Oryza sativa Japonica

Summary

OS02G0244100, also known as DA2 or GW2, encodes a RING-type zinc finger protein with ubiquitin ligase activity, placing it in the Sip5/DA2 protein family. The gene is associated with the regulation of seed size, grain weight, grain width, grain length, grain thickness, grain number, and overall grain yield. It has been linked to cell proliferation, cell division, organ growth, seed development, and grain filling. Additional associations include pre-harvest sprouting, seed dormancy, seed shattering, chlorophyll content and breakdown, leaf senescence, plant height, tiller number, days to heading, and stigma exsertion. The protein localizes to both the nucleus and cytoplasm and is linked to protein ubiquitination, nuclear export, and chromatin remodeling. Studies of related genes in other species link the family to organ size regulation.