Xa4 — Oryza sativa Indica Group

Summary

BGIOSGA040460 (symbol Xa4, also known as IWAK1) in Indica rice encodes a dual-specificity protein kinase with transmembrane receptor serine/threonine kinase activity, calcium ion binding, polysaccharide binding, and ubiquitin ligase activity. The protein contains EGF-like, WAK-like, and protein kinase domains. This gene is associated with cell surface receptor signaling, regulation of response to oxidative stress, salinity response, detection of symbiotic fungi, positive regulation of the hypersensitive response, and stomatal complex development and morphogenesis. It localizes to the external side of the plasma membrane and membrane. Xa4 is associated with blast disease resistance, defense responses, cell wall properties, and traits including sterility, dwarfism, panicle development, root development, anther development, and growth. Studies of related genes in other species connect the family to cold tolerance and chlorophyll content.