HAP4 — Oryza sativa Indica Group

Summary

BGIOSGA027539 (HAP4, also known as OiHAP4) on chromosome 8 of Indica rice encodes a protein containing ubiquitin and ubiquitin-like domains, with annotated molecular functions including histone methylase activity, thiol-dependent deubiquitinase activity, ubiquitin-protein transferase activity, and structural constituent of the ribosome. The gene is associated with diverse biological processes such as seed morphogenesis, seed dormancy, stomatal lineage progression, trichome branching, fruit and endosperm development, and responses to freezing, thermal stimulus, and salinity. It is linked to numerous agronomically important traits including grain weight, grain yield, grain shape, seed growth and development, flowering time, leaf senescence, root morphology, shoot branching, pollen fertility, and disease tolerance. The encoded protein localizes to the cytosolic ribosome, nucleolus, chromosome, and endosomal compartments. Studies of related genes in other species connect the family to salt tolerance, drought tolerance, cell proliferation, and temperature stress tolerance.