BIP — Oryza sativa Indica Group

Summary

BGIOSGA007251 (OiBIP) encodes a member of the Hsp70 family of ATP-dependent protein folding chaperones, containing a BIP_NBD domain and an HSP70 peptide-binding domain. In indica rice, this gene is associated with seed and endosperm phenotypes, and has been linked to grain yield per plant, spikelet number, spikelet fertility, and pollen fertility restoration. It is associated with responses to unfolded protein, ER stress, the ERAD pathway, protein refolding, and protein folding in the ER. Associations also include root hair length and development, leaf size and senescence, flowering time, auxin sensitivity, basipetal auxin transport, and abiotic stress responses including high and low temperature stress. The gene product localizes to the ER lumen, ER chaperone complex, transport vesicles, and the nuclear envelope. Related genes in other species link the family to cadmium stress tolerance and disease resistance.