TDP1 — Medicago truncatula

Summary

MTR_7G050860 (symbol TDP1, preferred name MtTDP1) on barrel medic chromosome 7 encodes a protein with 3'-tyrosyl-DNA phosphodiesterase activity, containing a SMAD_FHA_dom_sf and FHA domain. This gene is associated with programmed necrotic cell death, DNA metabolism, DNA damage response, DNA replication, cell cycle modulation, chromatin modeling, ribosome biogenesis, detoxification, response to copper, seed germination, seedling development, cell division, and cell death. The product localizes to the nucleus. Related genes in other species link the family to FHA domain-containing protein function. The gene is also associated with DNA repair and DNA-protein cross-link repair, and is related to BBR.