FL — Medicago truncatula

Summary

MTR_5G059130, designated FL and also known as MtFLS, encodes a protein with flavonol synthase activity, as well as leucocyanidin oxygenase, flavanone 4-reductase, dihydroflavanol 4-reductase, naringenin-chalcone synthase, and flavanone 3-dioxygenase activities, and belongs to the Fe2OG dioxygenase domain family. In barrel medic, this gene is associated with flavonol, anthocyanin, coumarin, and chalcone biosynthesis, auxin polar transport, nodulation, innate immunity, and responses to gravity, UV-B, jasmonic acid, wounding, oxidative stress, and light. It has been linked to traits including anthocyanin content, photosynthetic ability, flower development, pollen fertility restoration, herbicide sensitivity, root morphology, and tolerance to abiotic stresses such as salt, drought, low temperature, and UV light. The encoded protein localises to the cytosol, nucleus, endoplasmic reticulum, and tonoplast. Studies of related genes in other species connect the family to root gravitropic response, cyst nematode resistance, and flavonol synthesis.