RAD1 — Medicago truncatula
Summary
MTR_5G013480 (MtRAD1) on barrel medic chromosome 5 encodes a protein with an XPF nuclease domain and ERCC4 domain, possessing single-stranded DNA endonuclease activity. The gene is associated with nucleotide-excision repair of pyrimidine dimers, DNA repair, response to radiation and oxidative stress, hyphopodium formation, cutin anabolism, gibberellic acid signaling, root development, and homologous recombination repair. Its product localizes to the nucleus. MtRAD1 is associated with UV and ionizing radiation sensitivity and resistance phenotypes. Related genes in other species link the family to gamma radiation sensitivity, UV tolerance, homologous recombination, and fresh weight reduction upon crosslinker exposure.
Annotations
- Chromosome
- 5
- Related genes
- RAD1
- GO terms
- Hyphopodium Formation, GA-signaling, Response To Radiation, HDR, Response To Oxidative Stress, NER, Single-stranded DNA Endonuclease Activity, cutin anabolism
- Publications
- 19214203, 10394898, PMID:35861422, 21221633, PMID:9805401, PMID:28509359, PMID:25560877, PMID:29186498
- Traits
- UV sensitivity, gamma radiation sensitivity, ionizing radiation sensitivity, UV light sensitivity, radiation sensitivity, UV radiation sensitivity, Extreme Hypersensitivity to UV and Ionizing Radiation with Trichome Defects, Severe Fresh Weight Reduction When Exposed to Crosslinkers