BAS — Medicago truncatula

Summary

MTR_4G005270 (BAS) encodes a squalene cyclase with beta-amyrin synthase, lupeol synthase and camelliol C synthase activities, placing it in the terpenoid cyclase family. In barrel medic, this gene is associated with pentacyclic triterpenoid, saponin, sterol, alkaloid and indole alkaloid biosynthesis, as well as secondary metabolism and protein synthesis. It has been linked to responses to nitric oxide, hydrogen peroxide, ethylene, jasmonic acid, metal ions and fungal elicitors, and to nodulation. The encoded protein localises to the endoplasmic reticulum membrane, adiposome, mitochondria and nucleus. Associations with leaf necrosis and triterpene synthesis have been noted. Studies of related genes in other species link the family to lupeol, beta-amyrin and trinorlupeol biosynthesis, and to cuticular water barrier function.