CYP — Medicago truncatula

Summary

MTR_2G085075, designated MtCYP71, encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase with GTP cyclohydrolase II activity and cyclosporin A binding, and contains both cyclophilin and WD40 repeat domains. The gene is associated with diverse biological processes including sepal and leaf formation, trichome differentiation, stamen and carpel development, photoperiodism, chromatin silencing, and response to mannitol. It localizes to the nucleus, cytosol, chloroplast stroma, and chromatin-associated complexes such as CAF-1 and Cul4-RING E3 ubiquitin ligase. MtCYP71 is linked to traits including leaf necrosis, cell size, sulfur content, anthocyanin content, flowering time, drought tolerance, disease tolerance, and seed maturation. Related genes in other species are associated with genome stability, nucleosome assembly, meristem organization, and telomere maintenance.